Resources for Professionals
Stay informed with the latest scientific data on Abagen®, the anti-inflammatory peptide from blacklip abalone by Southern Ocean Biotech. Below, you’ll find downloadable resources, including the full patent and peer-reviewed studies, tailored for doctors and scientists exploring its potential in inflammatory disease treatment.
Therapeutic potential of abalone and status of bioactive molecules: A comprehensive review
Published in: Critical Reviews in Food Science and Nutrition (2017)
Summary: This review covers the therapeutic potential of bioactive compounds from abalone, detailing its anti-oxidant, anti-thrombotic, anti-inflammatory, anti-microbial, and anti-cancer activities. It also provides an overview of the abalone market and supply
Available Downloads
In vitro anti-inflammatory activities of blacklip abalone (Haliotis rubra) in RAW 264.7 macrophages
Published in: Food and Agricultural Immunology (2017)
Summary: This research found that an enzyme-derived extract from blacklip abalone viscera, particularly its unbound fractions, demonstrated significant anti-inflammatory activity. This was shown by inhibiting nitric oxide production in LPS-stimulated RAW 264.7 macrophage cells.
Anti-Coagulant and Anti-Thrombotic Properties of Blacklip Abalone (Haliotis rubra): In Vitro and Animal Studies
Published in: Marine Drugs (2017)
Summary: This study investigated an oral blacklip abalone extract in rats for anti-coagulant effects. While active in vitro and showing some clotting delay orally with no obvious harm, its low bioavailability suggests intravenous use might be more effective.
In vitro Anti-Thrombotic Activity of Extracts from Blacklip Abalone (Haliotis rubra) Processing Waste
Published in: Marine Drugs (2017)
Summary: Extracts from blacklip abalone processing waste, prepared with food-grade enzymes, showed anti-thrombotic activity due to their sulphated polysaccharide content. These extracts inhibited thrombin via heparin cofactor-II and displayed anti-coagulant effects in plasma and blood, which were enhanced by anion exchange chromatography.
In vitro anti-thrombotic and anti-coagulant properties of blacklip abalone (Haliotis rubra) viscera hydrolysate
Published in: Analytical and Bioanalytical Chemistry (2017)
Summary: A hydrolysate from blacklip abalone viscera exhibited in vitro anti-thrombotic activity through heparin cofactor II (HCII) and anti-coagulant effects in plasma and whole blood. Fractionation using chromatography significantly concentrated these properties, improving clotting time delays.
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